Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Norwalk virus vaccines: challenges and progress.

M K Estes1, J M Ball, R A Guerrero

  • 11Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA. mestes@bcm.tmc.edu.

The Journal of Infectious Diseases
|May 11, 2000
PubMed
Summary

Human caliciviruses (HuCVs) cause widespread gastroenteritis. Developing a vaccine for these viruses is challenging but crucial for preventing foodborne and waterborne illnesses.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequential therapy using high-dose esomeprazole-amoxicillin followed by gatifloxacin for Helicobacter pylori infection.

Alimentary pharmacology & therapeutics·2006
Same author

Rabeprazole containing triple therapy to eradicate Helicobacter pylori infection on the Texas-Mexican border.

Alimentary pharmacology & therapeutics·2006
Same author

In vivo tests of natural therapy, Tibetan yogurt or fresh broccoli, for Helicobacter pylori infection.

Methods and findings in experimental and clinical pharmacology·2005
Same author

Effect of different organic acids (citric, malic and ascorbic) on intragastric urease activity.

Alimentary pharmacology & therapeutics·2005
Same author

Novel bismuth-metronidazole-tetracycline triple-layer tablet for treatment of Helicobacter pylori.

Alimentary pharmacology & therapeutics·2005
Same author

Challenge model for Helicobacter pylori infection in human volunteers.

Gut·2004

Area of Science:

  • Virology
  • Immunology
  • Vaccinology

Background:

  • Human caliciviruses (HuCVs) are a primary cause of acute nonbacterial gastroenteritis globally.
  • Increasing recognition of HuCVs as significant foodborne and waterborne pathogens highlights the need for effective vaccines.

Purpose of the Study:

  • To review the challenges in developing a human calicivirus (HuCV) vaccine.
  • To outline the current status of candidate HuCV vaccine development.

Main Methods:

  • Review of existing literature on HuCV pathogenesis and vaccine development.
  • Analysis of challenges related to HuCV tropism and host range.

Main Results:

  • HuCVs exhibit restricted tropism for the human gastrointestinal tract.

Related Experiment Videos

  • A volunteer model for HuCV infection and disease is available for study.

    • Conclusions:

    • HuCVs serve as valuable models for studying gastrointestinal viral infections and mucosal immunity in humans.
    • Overcoming vaccine development challenges is essential for controlling HuCV-related diseases.