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[Cyclosporin in an oral microemulsion as the initial treatment of corticoid-refractory ulcerative colitis]
1Servicio de Medicina Digestiva, Hospital La Fe, Valencia. vicortiz@comv.es
Aim:
To assess the efficacy of oral microemulsion cyclosporin as the initial treatment of active ulcerative colitis refractory to steroid therapy.
Patients And Methods:
The evolution of five patients treated with a dose of 5 mg/kg/day was analyzed.
Results:
Oral microemulsion cyclosporin controlled acute attacks of the disease and led to remission during the 3 months of treatment in four of the five patients. Average hospital stay was 5.5 days.
Conclusions:
Oral microemulsion cyclosporin is an effective treatment in ulcerative colitis. Its administration is simple, the use of venous catheters is avoided and it may reduce mean hospital stay.
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