Related Experiment Video
Updated: Aug 24, 2026

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
Published on: July 24, 2021
[Infections with drug resistant bacteria and their treatment methods--VRE infections]
Abstract:
Vancomycin-resistant enterococci(VRE) is a worldwide threat now. Because we have lost a last resort vancomycin for enterococcal infections, and their resistant genes can be transferred to other more pathogenic gram-positive bacteria. We have only a few of optional therapeutic agents against VRE. VRE causes urinary tract infections, intra-abdominal infections, bacteremias, endocarditis and wound infections. Especially bacteremias caused by VRE result in high mortality. VRE infections including colonization and infectious diseases must be controlled by rapid detection of VRE, appropriate diagnosis of infections, followed by effective antimicrobial therapies and infection control measures.
Insights
Vancomycin-resistant enterococci (VRE) pose a global health threat due to limited treatment options. Effective control requires rapid detection, diagnosis, and antimicrobial therapies for VRE infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Context:
- Vancomycin-resistant enterococci (VRE) represent a significant global health challenge.
- The emergence of VRE limits therapeutic options for enterococcal infections, as vancomycin is often ineffective.
- VRE can transfer resistance genes to other pathogenic bacteria, exacerbating the threat.
Purpose:
- To highlight the critical nature of Vancomycin-resistant enterococci (VRE) infections.
- To emphasize the need for comprehensive strategies to combat VRE.
- To underscore the importance of rapid detection and effective treatment of VRE.
Summary:
- VRE infections, including bacteremia, urinary tract infections, and endocarditis, are associated with high mortality rates.
- The limited availability of effective antimicrobial agents necessitates stringent infection control measures.
- Control strategies must encompass rapid VRE detection, accurate diagnosis, appropriate antimicrobial therapies, and robust infection control protocols.
Impact:
- Improved understanding of the VRE threat and its implications for public health.
- Potential for enhanced clinical management and infection control strategies.
- Highlights the urgent need for novel therapeutic approaches and continued surveillance of VRE.
More Related Videos
Related Concept Videos
Antibiotic Selection
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Acute Pyelonephritis II: Diagnostic Studies and Management
Development of Antibiotic Resistance
Mechanism of Antibiotic Resistance in MRSA
Clinical Significance of Antibiotic Resistance

