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[Chemical reactions catalyzed by DNA polymerases]
1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Bioorganicheskaia Khimiia
|May 12, 2000
Abstract:
Chemical reactions catalyzed by various DNA polymerases are discussed, including DNA chain extension, the 3'-->5'-exonuclease proofreading activity, and some other pathways of replicative repair. The contribution of DNA polymerases to the fidelity of the template-dependent synthesis is analyzed by the examples of some most typical DNA polymerases.