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Surgery for cardiac myxomas.

H V Schaff1, C J Mullany

  • 1Division of Cardiovascular Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.

Seminars in Thoracic and Cardiovascular Surgery
|May 12, 2000
PubMed
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Left-atrial myxomas are common primary heart tumors. Surgical removal is safe, curative, and offers excellent long-term survival with a low recurrence rate, especially when familial forms are recognized.

Area of Science:

  • Cardiovascular Surgery
  • Oncology
  • Cardiology

Background:

  • Myxomas, especially left-atrial myxomas, are the most frequent primary cardiac tumors requiring surgical intervention.
  • These tumors can cause symptoms through inflammatory mediators, blood flow obstruction, or embolization.
  • Most cardiac myxomas are benign, with surgical excision being a safe and effective treatment.

Purpose of the Study:

  • To review the Mayo Clinic's 38-year experience with cardiac myxoma surgery.
  • To assess the safety, efficacy, and long-term outcomes of myxoma excision.
  • To highlight the importance of identifying familial and syndrome-associated myxomas.

Main Methods:

  • Retrospective review of 100 patients undergoing 106 operations for cardiac myxoma over 38 years.

Related Experiment Videos

  • Analysis of perioperative mortality, long-term survival, and recurrence rates.
  • Evaluation of the impact of familial and syndrome myxomas on management and outcomes.

    • Main Results:

    • A single perioperative death occurred in 106 operations.
    • Long-term survival post-excision is comparable to the general population.
    • At 20 years, 94% of patients remained free of recurrent myxomas.

    Conclusions:

    • Surgical excision of cardiac myxomas is associated with excellent short- and long-term outcomes.
    • Recognizing familial and syndrome myxomas is crucial for tailored surgical approaches and follow-up.
    • Cardiac myxoma surgery offers a curative option with a low risk of recurrence.