Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Malignancies involving the pericardium.

W H Warren1

  • 1Department of Cardiovascular-Thoracic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612, USA.

Seminars in Thoracic and Cardiovascular Surgery
|May 12, 2000
PubMed
Summary

Malignant pericardial effusions, often from secondary cancers, cause significant symptoms. Subxiphoid pericardiostomy offers safe and effective relief for terminally ill patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mixed control for perception and action: timing and error correction in rhythmic ball-bouncing.

Experimental brain research·2013
Same author

A multi-analyte serum test for the detection of non-small cell lung cancer.

British journal of cancer·2010
Same author

The dynamics of gait transitions: effects of grade and load.

Journal of motor behavior·2009
Same author

Coupling of posture and gait: mode locking and parametric excitation.

Biological cybernetics·2001
Same author

Optic flow is used to control human walking.

Nature neuroscience·2001
Same author

Perception of heading during rotation: sufficiency of dense motion parallax and reference objects.

Vision research·2000

Area of Science:

  • Oncology
  • Cardiology
  • Thoracic Surgery

Background:

  • Malignancies rarely originate in the pericardium; mesothelioma is the most common primary type.
  • Secondary pericardial involvement by cancer is more frequent, occurring via direct extension, lymphangitic spread, or hematogenous dissemination.
  • These secondary malignancies often present as symptomatic pericardial effusions, sometimes leading to cardiac tamponade.

Purpose of the Study:

  • To review the presentation and management of malignant pericardial effusions.
  • To evaluate the efficacy and safety of different surgical interventions for pericardial malignancies.
  • To guide therapeutic decisions based on the origin and extent of pericardial involvement.

Main Methods:

  • Review of literature on pericardial malignancies and their management.
  • Analysis of clinical presentations, including pericardial effusion and tamponade.
  • Evaluation of surgical techniques such as subxiphoid pericardiostomy and open procedures.

Main Results:

  • Primary pericardial mesothelioma is typically unresectable and incurable.
  • Lung carcinoma and thymoma invading the pericardium may be curatively resectable with adjuvant therapy.
  • Subxiphoid pericardiostomy is a safe and effective palliative procedure for symptomatic effusions in terminally ill patients.

Conclusions:

  • Malignant pericardial effusions require careful management tailored to the underlying malignancy.
  • Palliative drainage procedures like subxiphoid pericardiostomy are crucial for symptom control in advanced disease.
  • Aggressive surgical approaches are reserved for specific cases of loculated or recurrent effusions.

Related Experiment Videos