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Treatment of HIV disease in the new millennium

V Kak1, R D MacArthur, L R Crane

  • 1Department of Internal Medicine, Wayne State University, Detroit, MI 48201, USA.

Seminars in Thoracic and Cardiovascular Surgery
|May 12, 2000
PubMed

Highly active antiretroviral therapy (HAART), which typically consists of 3-drug combinations of antiretroviral agents, has decreased dramatically the incidence of AIDS and death among HIV-infected persons in the United States. HIV infection no longer is viewed as a death sentence. Complete suppression of viral replication through the use of HAART can reverse the immune deficits formerly thought to be inevitable. However, drug toxicity, cross-resistance, and less-than-perfect adherence to prescribed antiretroviral regimens make the medical management of the HIV-infected person complex. An overview of the current approach to antiretroviral therapy is presented in this article.

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