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[The synthesis of galactopyranosyl-substituted derivatives of pheophorbide]
A A Aksenova1, Iu L Sebiakin, A F Mironov
1Lomonosov State Academy of Fine Chemical Technology, Moscow, Russia.
Bioorganicheskaia Khimiia
|May 16, 2000
Abstract:
New pheophorbide and pyropheophorbide derivatives containing carbohydrate fragments, derivatives of galactopyranose, were synthesized. Galactopyranosylpheophorbide and galactopyranosylpyropheophorbide with free hydroxyl groups were found to be water-soluble and useful as sensitizers in photodynamic therapy of cancer.