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Updated: Jul 16, 2026

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Preparation of Peripheral Nerve Stimulation Electrodes for Chronic Implantation in Rats
Published on: July 14, 2020
Pain suppression by peripheral nerve stimulation. Part II. Observations with implanted devices
Surgical Neurology
|July 1, 1975
Summary
This study shows that implanting a stimulator system provided significant pain relief for most patients. The treatment was effective, reproducible, and led to reduced medication use and better social functioning.
Area of Science:
- Neurology
- Neurosurgery
- Pain Management
Background:
- Chronic pain significantly impacts patient quality of life.
- Current pain management strategies have limitations.
- Neuromodulation offers a potential therapeutic avenue.
Purpose of the Study:
- To evaluate the efficacy and safety of a stimulator system for pain relief.
- To assess the impact of the stimulator system on drug intake and social performance.
- To analyze surgical techniques and complications associated with the implantation.
Main Methods:
- Implantation of a stimulator system in 23 patients.
- Follow-up period ranging from 6 to 20 months.
- Assessment of pain relief, drug intake, and social performance.
Main Results:
- Twenty out of 23 patients reported 50% to 100% pain relief.
- The observed pain relief was consistent and reproducible.
- Significant reduction in drug intake and improvement in social performance were noted.
Conclusions:
- The stimulator system demonstrates high efficacy in managing chronic pain.
- The procedure is associated with favorable outcomes, including reduced medication reliance and enhanced social functioning.
- The study provides insights into surgical techniques and potential complications.

