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Urinary beta-glucuronidase in renal cell carcinoma
A Rodríguez-Cuartero1, F Barcelona-Martín, F J Pérez-Blanco
1Department of Internal Medicine, San Cecilio University Hospital and Mora Lara Medical Research Centre, University of Granada, Spain.
Abstract:
The aim of the paper was to study the urinary beta-glucuronidase activity in 30 patients with renal cell carcinoma (RCC), histopathologically proven after surgery, and 32 healthy subjects taken as controls. Classification of patients was done using the TNM system. A statistically significant increase (p < 0.01) in this enzyme was found in RCC patients, without relation to the changes in the urinary sediment (hematuria, pyuria, bacteriuria) or tumor dissemination. Urinary beta-glucuronidase is a useful marker in the diagnosis of malignant renal tumors.
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