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Syringomyelia complicating syphilitic spinal meningitis: a case report
K K Bulundwe1, C J Myburgh, R F Gledhill
1Department of Neurology, MEDUNSA/Ga-Rankuwa and Pedimed Hospital, Reitfontein, South Africa.
European Journal of Neurology
|May 16, 2000
Abstract:
An association between syringomyelia and spinal syphilis was described in the early literature but has not been the subject of reports subsequently. We give details of a contemporary case, affirmed by magnetic resonance imaging. The patient showed significant clinical recovery following penicillin treatment, while the imaging appearances became less pronounced.
Insights
Syringomyelia associated with spinal syphilis is rare but treatable. A contemporary case showed significant recovery with penicillin, improving both clinical symptoms and MRI findings.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Syringomyelia and spinal syphilis were historically linked but rarely reported in modern literature.
- This association highlights the importance of considering neurosyphilis in syringomyelia cases.
Purpose of the Study:
- To report a contemporary case of syringomyelia secondary to spinal syphilis.
- To document the clinical and radiological outcomes following antibiotic treatment.
Main Methods:
- Magnetic resonance imaging (MRI) was used to diagnose and monitor the condition.
- Treatment with penicillin was administered to the patient.
Main Results:
- The patient presented with clinical symptoms consistent with syringomyelia.
- MRI confirmed the presence of syringomyelia.
- Significant clinical improvement was observed post-penicillin therapy.
- Radiological findings on MRI showed a reduction in the severity of syringomyelia.
Conclusions:
- Spinal syphilis should be considered in the differential diagnosis of syringomyelia.
- Early diagnosis and treatment with penicillin can lead to substantial recovery.
- This case underscores the resurgence of syphilis and its diverse neurological manifestations.
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