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Published on: March 8, 2017
Intratympanic and systemic dexamethasone for Ménière's disease
T P Hirvonen1, M Peltomaa, J Ylikoski
1Department of Otorhinolaryngology, Helsinki University Central Hospital, Helsinki, Finland. timo.hirvonen@huch.fi
Summary
Intratympanic and systemic dexamethasone did not significantly improve Ménière
Area of Science:
- Otolaryngology
- Neurology
Background:
- Ménière's disease (MD) is a chronic inner ear disorder.
- Current treatments for MD have limitations.
Purpose of the Study:
- To evaluate the efficacy of intratympanic and systemic dexamethasone for Ménière's disease.
Main Methods:
- Prospective study of 17 MD patients.
- Treatment involved intratympanic dexamethasone injections and an initial intramuscular injection.
- Patients were followed for 1 year with audiometry and symptom scales.
Main Results:
- No significant improvement in aural fullness, hearing loss, tinnitus, or vertigo.
- Sufficient vertigo control was achieved in 76% of patients.
Conclusions:
- Intratympanic and systemic dexamethasone showed no definite treatment effect for MD.
- Further investigation is needed for clinical use of dexamethasone in MD.
