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Risperidone side effects.

R R Conley1

  • 1Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore 21228, USA.

The Journal of Clinical Psychiatry
|May 16, 2000
PubMed
Summary
This summary is machine-generated.

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Risperidone, an atypical antipsychotic, shows fewer motor side effects and less weight gain than traditional antipsychotics. Clinicians should monitor for adverse events, including elevated prolactin levels, in patients on risperidone.

Area of Science:

  • Psychiatry
  • Pharmacology

Background:

  • Traditional antipsychotics for schizophrenia cause extrapyramidal side effects, leading to poor adherence.
  • Atypical antipsychotics offer an alternative, but data on their adverse events are limited.

Purpose of the Study:

  • To review the adverse event profile of risperidone, a combined 5-HT2/D2 antagonist.
  • To compare risperidone's side effects with those of traditional antipsychotics and other atypical agents.

Main Methods:

  • Literature review focusing on adverse events associated with risperidone.
  • Comparison of side effect profiles across different antipsychotic classes.

Main Results:

  • Risperidone is associated with minimal motor side effects compared to traditional antipsychotics.

Related Experiment Videos

  • Weight gain is less common with risperidone than with clozapine or olanzapine.
  • Increased prolactin levels are reported but show little correlation with adverse events.

    • Conclusions:

    • Risperidone presents a favorable side effect profile regarding motor symptoms and weight gain.
    • Clinicians must remain vigilant for potential adverse events, including hyperprolactinemia, with atypical antipsychotics like risperidone.