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A case of hypothalamic adrenal insufficiency manifested normal ACTH response to insulin-induced hypoglycemia
1The First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Japan.
Endocrine Journal
|May 16, 2000
Abstract:
A low plasma ACTH response to insulin-induced hypoglycemia and an exaggerated and delayed plasma ACTH response to CRH stimulation have been considered as an indicator of hypothalamic hypopituitarism. We report a case of hypothalamic adrenal insufficiency which manifested normal ACTH response to insulin-induced hypoglycemia. This case provides important information to categorize hypothalamic adrenal insufficiency caused by abnormal regulation of CRH release.