A role for P-glycoprotein in regulating cell death

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Updated: Oct 16, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
09:18

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

R W Johnstone1, A A Ruefli, K M Tainton

  • 1Cellular Cytotoxicity Laboratory, The Austin Research Institute, Australia, Victoria. r.johnstone@ari.unimelb.edu.au

Leukemia & Lymphoma
|May 16, 2000
PubMed

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
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