Related Experiment Videos
Diagnostic radiation oncology: malignant cystosarcoma phylloides
P D Eich1, S Diederich, H T Eich
1Institut für Klinische Radiologie, Westfälische Wilhelms-Universität Münster, Germany. ikr@uni-muenster.de
Summary
Cystosarcoma phylloides, a rare breast tumor, can be radiosensitive. Postoperative radiation therapy is recommended to prevent local recurrences of this challenging malignancy.
Area of Science:
- Oncology
- Surgical Oncology
- Radiation Oncology
Background:
- Cystosarcoma phylloides is a rare breast tumor, often benign, typically treated with surgical excision.
- High local recurrence rates (up to 46%) are observed despite complete resection.
- Radiotherapy is infrequently reported but indicated for recurrent or metastatic disease.
Observation:
- A 54-year-old woman presented with a large cystosarcoma phylloides and axillary lymph node metastases.
- Despite complete resection (R0), she experienced multiple thoracic wall, pulmonary, and pleural recurrences.
- Initial polychemotherapy showed a response, but disease progressed, necessitating radiation therapy.
Findings:
- Radiation therapy (50 Gy) to the right thoracic wall resulted in a significant clinical response.
- The patient remained recurrence-free for 5 months post-radiation.
- This case suggests cystosarcoma phylloides exhibits radiosensitivity.
Implications:
- Postoperative radiation therapy may be a crucial strategy to prevent local recurrences in cystosarcoma phylloides.
- This finding supports the consideration of radiotherapy in the management of recurrent or refractory cases.
- Further research into the role of radiation in cystosarcoma phylloides is warranted.