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Updated: Oct 16, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
[Increased occurrence of autoimmune thyroiditis in patients with chronic rheumatoid arthritis]
R Pongratz1, W Buchinger, G Semlitsch
1Internen Abteilung des Krankenhauses der Barmherzigen Brüder, Eggenberg, Graz. rheuma.ambulanz@bbegg.at
Abstract:
The frequent occurrence of both rheumatoid arthritis and autoimmune thyroiditis was already investigated with in part many conflicting results. We investigated a number of 792 patients (383 of them suffering from rheumatoid arthritis and 409 with osteoarthritis). In all patients antithyroid peroxidase and antithyroglobulin antibodies were determined. Patients with rheumatoid arthritis showed a significantly higher occurrence of circulating thyroid antibodies than those with osteoarthritis (9.1% versus 3.7%, p = 0.0016). We conclude that there exists a cumulate coincidence of both diseases. Patients suffering from rheumatoid arthritis should undergo a thyroid examination especially for the presence of autoimmune thyroiditis.
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