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Ulcerative colitis with sagittal sinus thrombosis with normal coagulation profile.
1Department of Medicine, Lady Hardinge Medical College, New Delhi. sanjaybansal@hotmail.com
Summary
Thromboembolic events, like sagittal sinus thrombosis, can complicate inflammatory bowel diseases. Subcutaneous heparin effectively treated a patient with ulcerative colitis and this rare complication, even with a normal coagulation profile.
Area of Science:
- Gastroenterology
- Hematology
- Neurology
Background:
- Inflammatory bowel diseases (IBD), including ulcerative colitis, are associated with an increased risk of thromboembolic events.
- Cerebral venous sinus thrombosis (CVST) is a rare but serious complication of IBD.
Observation:
- A 30-year-old male patient with ulcerative colitis presented with symptoms of sagittal sinus thrombosis.
- The patient's coagulation profile was within the normal range, despite the presence of thrombosis.
Findings:
- Diagnosis of sagittal sinus thrombosis was confirmed in the patient with ulcerative colitis.
- Treatment with subcutaneous heparin led to clinical remission of the ulcerative colitis symptoms.
Implications:
- This case highlights the importance of considering CVST in IBD patients presenting with neurological symptoms.
- Subcutaneous heparin may be an effective treatment for CVST in IBD patients, even with normal coagulation parameters.
- Further research is warranted to understand the pathophysiology and optimal management of CVST in IBD.