Related Experiment Video
Updated: Aug 6, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Human metabolic pathways of dietary flavonoids and cinnamates
G Williamson1, A J Day, G W Plumb
1Institute of Food Research, Norwich Research Park, Colney, UK.
Abstract:
Flavonoids and cinnamates are widespread phenolic secondary metabolites synthesized by plants for defensive purposes. Many foods and beverages contain high levels of phenolic compounds. Certain phenolics in the diet are particularly bioactive and have pronounced effects on mammalian cells. These effects, together with epidemiological studies and animal models, have led to the hypothesis that dietary phenolics contribute to the health benefits of a diet rich in fruit and vegetables. This paper examines the biochemistry of the uptake and metabolic route of two groups of plant phenolics, the flavonols and hydroxycinnamates.
Related Concept Videos
Dietary Connections
Cancer Prevention
Some...
Phase I Reactions: Oxidation of Aliphatic and Aromatic Carbon-Containing Systems
Oxidation reactions are fundamental in aromatic carbon-containing systems. An example is the hydroxylation of phenobarbital, a process that transforms it into...
Pharmacogenetics of Phase I Enzymes: Cytochrome P450 Isozymes
Introduction to Metabolism
Amino Acid Biosynthetic Pathways

