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Detection of 23 immunogenic pneumococcal proteins using convalescent-phase serum
G Zysk1, R J Bongaerts, E ten Thoren
1Department of Medical Microbiology and Virology, University of Duesseldorf, Duesseldorf, Germany. zysk@uni-duesseldorf.de
Infection and Immunity
|May 19, 2000
Abstract:
A genomic expression library of Streptococcus pneumoniae was screened with a convalescent-phase serum for immunoreactive proteins. Six known and 17 unknown pneumococcal proteins were detected. Five of the known proteins were surface-located virulence factors, and eight of the unknown proteins were putative membrane proteins.