Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Brugada's syndrome].

R Grolleau1, F Leclercq, J L Pasquie

  • 1Service de cardiologie A, hôpital Arnaud-de-Villeneuve, Montpellier.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|May 19, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Speech audiometry in noise: SNR Loss per age-group in normal hearing subjects.

European annals of otorhinolaryngology, head and neck diseases·2021
Same author

Guidelines of the French Society of Otorhinolaryngology-Head and Neck Surgery (SFORL) and the French Society of Audiology (SFA) for Speech-in-Noise Testing in Adults.

European annals of otorhinolaryngology, head and neck diseases·2021
Same author

Respiratory syncytial virus-associated mortality in a healthy 3-year-old child: a case report.

BMC pediatrics·2019
Same author

[TAVI simplification: A focus].

Annales de cardiologie et d'angeiologie·2019
Same author

The multiple merger assembly of a hyperluminous obscured quasar at redshift 4.6.

Science (New York, N.Y.)·2018
Same author

Author Correction: Nearly all the sky is covered by Lyman-α emission around high-redshift galaxies.

Nature·2018
Same journal

Radiokymographic study of the kinetics of the middle arc and the hils in the normal subject.

Archives des maladies du coeur et des vaisseaux·2010
Same journal

A medication for angina pectoris and pre-fibrillatory conditions; 1262 F; six years of clinical experience; action mechanism.

Archives des maladies du coeur et des vaisseaux·2010
Same journal

Circulatory changes following the injection of hypertonic saline solutions; application to the study of angina pectoris.

Archives des maladies du coeur et des vaisseaux·2010
Same journal

Alterations in coronary circulation during aortic insufficiency in young subjects.

Archives des maladies du coeur et des vaisseaux·2010
Same journal

Cardio-esophageal auscultation.

Archives des maladies du coeur et des vaisseaux·2010
Same journal

Hypertensive accidents following the injection of acetylcholine.

Archives des maladies du coeur et des vaisseaux·2010
See all related articles

Idiopathic ventricular fibrillation can cause sudden cardiac death. The Brugada syndrome, characterized by specific ECG changes and ventricular fibrillation in patients without heart disease, is a key focus in understanding these electrical abnormalities.

Area of Science:

  • Cardiology
  • Genetics
  • Electrophysiology

Context:

  • Ventricular fibrillation (VF) is a known complication of cardiac diseases, but some cases remain idiopathic despite thorough investigation.
  • Congenital long QT syndrome demonstrates that purely electrical abnormalities can lead to syncope and sudden death, with increasing understanding of their ionic and genetic bases.
  • The Brugada syndrome, identified in 1991, presents with distinct electrocardiographic patterns (right bundle branch block, ST elevation in V1-V3) and is associated with VF in individuals without structural heart disease.

Purpose:

  • To explore the concept of purely arrhythmic abnormalities as a cause of sudden cardiac death.
  • To investigate the link between specific electrocardiographic findings and underlying ionic and genetic mechanisms.
  • To shed light on the etiology of idiopathic ventricular fibrillation, particularly in the context of Brugada syndrome.

Related Experiment Videos

Summary:

  • The Brugada syndrome is a distinct clinical entity characterized by specific ECG findings and a propensity for ventricular fibrillation in the absence of apparent heart disease.
  • This syndrome shares similarities with congenital long QT syndrome, highlighting the role of electrical abnormalities in sudden cardiac death.
  • Research is advancing our understanding of the sequence from ECG manifestations to the ionic and genetic underpinnings of Brugada syndrome.

Impact:

  • Advances understanding of the genetic and ionic basis of cardiac arrhythmias.
  • Improves diagnosis and management strategies for patients at risk of sudden cardiac death.
  • Contributes to the broader field of electrocardiology and the study of channelopathies.