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Analysis of salbutamol and related impurities by derivative spectrometry
1Biological & Medical Research Department (MBC-03), King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Archiv Der Pharmazie
|May 19, 2000
Abstract:
Ultraviolet derivative spectrometry has been proposed for the analysis of salbutamol and related impurities. The assay of salbutamol aldehyde, 5-formyl-saligenin, and salbutamol ketone was performed in sodium hydroxide 0.1 mol/l solutions, using first and second derivative spectra. The method has been applied for the assay of related impurities of commercial samples of salbutamol sulfate.