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Leukocyte subsets in treatment-resistant major depression
M Kubera1, D Van Bockstaele, M Maes
1Department of Endocrinology, Institute of Pharmacology, Polish Academy of Sciences, Kraków.
Patients with treatment-resistant major depression had a significantly higher percentage of helper CD4+ T cells and immature double positive CD4+CD8+ T cells in their blood, and higher CD4+/CD8+ ratio than healthy controls. These results suggest activation of T helper immuno-response and disturbance in thymus function in these patients.
Patients with treatment-resistant major depression had a significantly higher percentage of helper CD4+ T cells and immature double positive CD4+CD8+ T cells in their blood, and higher CD4+/CD8+ ratio than healthy controls. These results suggest activation of T helper immuno-response and disturbance in thymus function in these patients.