Related Experiment Videos
Animal model of Alzheimer-like vascular pathology and inflammatory reaction
1Department of Anatomy, College of Medicine, University of South Florida, Tampa 33612, USA. jrhodin@com1.med.usf.edu
Annals of the New York Academy of Sciences
|May 20, 2000
Abstract:
This in vivo animal model of vascular inflammatory reaction facilitates morphologic and hemodynamic analyses of leukocyte-endothelial interaction and can be monitored by video microscopy and electron microscopy. The model has served as a rapid means to explore the deleterious vascular actions and inflammatory response to the cytokines tumor necrosis factor, interleukin-1 and amyloid-beta, as well as the protective effects of superoxide dismutase, estrogen, and cytokine antagonists.