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An azaanthracene alkaloid from Polyalthia suberosa
P Tuchinda1, M Pohmakotr, B Munyoo
1Department of Chemistry, Faculty of Science, Mahidol University, Bangkok, Thailand. scptc@mahidol.ac.th
Phytochemistry
|May 23, 2000
Summary
A novel azaanthracene alkaloid, kalasinamide, was isolated from Polyalthia suberosa stems. This study also identified known compounds, N-trans-feruloyltyramine and N-trans-coumaroyltyramine, using spectroscopic analysis.
Area of Science:
- Natural Product Chemistry
- Phytochemistry
- Organic Chemistry
Background:
- Polyalthia suberosa is a plant species known for its potential medicinal properties.
- Alkaloids and other secondary metabolites are often investigated for their unique chemical structures and biological activities.
Purpose of the Study:
- To isolate and characterize chemical constituents from the stems of Polyalthia suberosa.
- To identify novel or known compounds from this plant source.
Main Methods:
- Phytochemical investigation involving isolation techniques.
- Structure elucidation using spectroscopic methods (e.g., NMR, Mass Spectrometry).
Main Results:
- Isolation of a new azaanthracene alkaloid, identified as 1-aza-9,10-dimethoxy-4-methyl-2-oxo-1,2-dihydroanthracene (kalasinamide).
- Identification of two known compounds: N-trans-feruloyltyramine and N-trans-coumaroyltyramine.
- Confirmation of structures through comprehensive spectroscopic data analysis.
Conclusions:
- The stems of Polyalthia suberosa contain a diverse range of chemical compounds, including a novel alkaloid.
- This research contributes to the understanding of the phytochemical profile of Polyalthia suberosa.
- The identified compounds may warrant further investigation for potential pharmacological activities.