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Total syntheses of (+/-)-preussomerins G and I
1Department of Chemistry, University of California, Berkeley 94720, USA.
Organic Letters
|May 24, 2000
Abstract:
[formula: see text] Preussomerins G and I (2 and 3) have been synthesized for the first time. The key reaction in the synthesis is a possibly biomimetic tautomerization reaction depicted in Scheme 3 and the foregoing graphic. The driving force for this interesting rearrangement is primarily derived from the increase in resonance energy associated with converting a naphthalene ring into two isolated benzene rings.