[Disorders of central hemodynamics and water-salt metabolism in miners in deep coal mines]

In a study into the condition of central hemodynamics and water-salt metabolism made in 85 essentially healthy underground miners working in a coal mine those miners greater than 40 years old exhibited an increase in the peripheral vascular resistance together with a decrease in the power of the left ventricle and a rise in energy expenditure on blood redirection, which fact led to lowering of both volume- and velocity-related parameters for hemodynamics. Worsening of hemodynamic indexes was noted to be going on parallel to changes in water-salt metabolism: workers beyond thirty years of age showed an augmentation of the level of Na+ and creatinine in blood plasma, those greater than 40 years old demonstrated a reduction in urine creatinine, in those beyond fifty years of age glomerular filtration rate was found to be on decrease with fractional excretion of Na+ being on the increase.