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Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
Published on: May 6, 2014
[Changes in guidelines for the therapy of non-nosocomial pneumonitis]
1Dipartimento di Biologia molecolare, Università della California, Berkeley 94720-3200, USA.
Abstract:
In the USA therapeutic suggestions for a more appropriate treatment of community acquired pneumonias, are presently under revision. In this review we underline the difficulties encountered today, at the beginning of the year 2000, in the formulation of appropriate guidelines for this disease, taxed just about constantly by a mortality rate of nearly 8%. We emphasized the problem of bacterial resistance to multiple antibiotics and the frequency of polymicrobial pulmonary infections with an obvious worsening of the prognostic outlook. Directions about choice and use of some antibiotics have been provided, citing especially the fluoroquinolones and the more recent one, the moxifloxacine. A recommendation is given as well to pharmaceutical companies for them to provide better directives about the ideal modalities of administration of new antibiotics with the double aim of helping patients and also attempt to prevent onset of bacterial resistance.
Insights
Formulating guidelines for community-acquired pneumonia is challenging due to high mortality and increasing antibiotic resistance. New fluoroquinolones like moxifloxacin offer treatment options, but responsible antibiotic use is crucial.
Area of Science:
- Infectious Diseases
- Pulmonology
- Pharmacology
Context:
- Community-acquired pneumonia (CAP) treatment guidelines in the USA are under revision.
- CAP presents significant challenges with an 8% mortality rate.
- Prevalence of antibiotic resistance and polymicrobial infections complicates CAP management.
Purpose:
- To review current challenges in formulating CAP treatment guidelines.
- To discuss the impact of bacterial resistance and polymicrobial infections on CAP prognosis.
- To provide recommendations on antibiotic selection and administration for CAP.
Summary:
- The review highlights difficulties in establishing CAP treatment guidelines due to high mortality and resistance.
- Bacterial resistance and polymicrobial infections worsen CAP outcomes.
- Fluoroquinolones, including moxifloxacin, are discussed as therapeutic options.
Impact:
- Offers insights into current CAP management challenges.
- Provides guidance on antibiotic choice and use for CAP.
- Recommends improved antibiotic administration guidelines to combat resistance and aid patient care.
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