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Updated: Aug 16, 2026

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice
Published on: December 18, 2015
From cell lineage to developmental genetics
1CRATS, URA 1743 (CNRS) Université Ch. De Gaulle, Lille III, France.
Abstract:
One of the bases of developmental genetics resides in the alliance of clonal analysis and genetic analysis. But the study of cell lineage--cells which have their genealogical relationship--and the study of the cellular labelled progeny, have their own history. We have tried to follow it since its foundation with C.O. Whitman (1878) and E.B. Wilson (1892). A.H. Sturtevant (1929) and C. Stern (1936) the first tools to study the 'cell lineage' in Drosophila. We stress the contribution of the pioneer work realised around 1940. In the following period we witness the emergence of developmental genetics in Drosophila mainly with E. Hadorn (1949-1966), C. Stern (1954-1968) and E.B. Lewis (1963-1964). We conclude with A. Garcia-Bellido's view of compartments: supra-cellular units of development (1973). A postscript presents the most recent publications and some critical focuses.
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