Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The vertebral end-plate: what do we know?

R J Moore1

  • 1Institute of Medical and Veterinary Science, Department of Pathology, University of Adelaide, Australia. rob.moore@imvs.sa.gov.au

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
|May 24, 2000
PubMed
Summary

The vertebral end-plate is vital for intervertebral disc health. This review details how end-plate changes from aging and pathology impact spinal function and disc integrity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Data of soil, vegetation and bird species found on double-crested cormorant colonies in the southeastern United States.

Data in brief·2019
Same author

A gut reaction: the combined influence of exercise and diet on gastrointestinal microbiota in rats.

Journal of applied microbiology·2017
Same author

Binding of Clostridium perfringens to collagen correlates with the ability to cause necrotic enteritis in chickens.

Veterinary microbiology·2015
Same author

Examination of the antibacterial properties of sphagnum moss (Sphagnum spp.) and its significance with turf burning in Ireland.

British journal of biomedical science·2013
Same author

Changes in osteocyte density correspond with changes in osteoblast and osteoclast activity in an osteoporotic sheep model.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2011
Same author

Osteopenia in the maxillofacial area: a study in sheep.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2010

Area of Science:

  • Spinal Health
  • Orthopedics
  • Biomedical Engineering

Background:

  • The vertebral end-plate is essential for maintaining intervertebral disc (IVD) health.
  • Degenerative changes and pathologies significantly affect IVD integrity.
  • Understanding end-plate structure and function is crucial for spinal health research.

Purpose of the Study:

  • To review existing literature on vertebral end-plate structure and development.
  • To describe the impact of aging and pathology on end-plate function.
  • To illustrate the role of the end-plate in overall spinal function.

Main Methods:

  • Literature review of biomechanical, biochemical, surgical, and histological studies.
  • Analysis of changes associated with aging and pathology.

Related Experiment Videos

  • Synthesis of data to demonstrate end-plate's role in spinal function.

    • Main Results:

    • The vertebral end-plate plays a critical role in maintaining intervertebral disc health.
    • Changes in the end-plate due to aging and pathology compromise disc integrity.
    • Diverse study methodologies confirm the end-plate's significance in spinal biomechanics.

    Conclusions:

    • The vertebral end-plate is indispensable for spinal health.
    • Pathological and aging-related alterations of the end-plate have profound effects on the intervertebral disc.
    • Further research into end-plate function is vital for understanding and treating spinal disorders.