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Translational frameshift sites within bacteriophage lambda genes rexA and cI
1Department of Microbiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Acta Biochimica Polonica
|May 29, 2000
Abstract:
Phage lambda's cI-rexA-rexB operon displays an intriguing example of regulation by an unexplained mechanism of polarity. We have identified three potential -1 translational frameshift sites and present a model for translational frameshift suppression by lambda's CI repressor as a mechanism of regulating operon polarity, implying an additional role for CI self-regulation.