Comparison of genetically engineered microbial and plant phytase for young broilers.

Area of Science:

• Animal Nutrition
• Biotechnology
• Feed Additives

Background:

• Phytate phosphorus (P) is a major P source in plant-based broiler diets but has low bioavailability.
• Phytase enzymes are used to improve phytate P utilization and reduce inorganic P supplementation.
• Evaluating novel phytase sources like Phytaseed is crucial for optimizing broiler nutrition.

Purpose of the Study:

• To compare the efficacy of microbial (Natuphos) and plant-derived (Phytaseed) phytase in enhancing phytate P utilization in broilers.
• To assess the safety of Phytaseed phytase in young broiler diets.
• To determine the dose-response relationship for phytase supplementation.

Main Methods:

• Corn-soybean meal basal diets with varying levels (250, 500, 2,500 U/kg) of Natuphos and Phytaseed phytase were fed to broilers.
• Growth performance (body weight gain, feed intake, gain:feed) was monitored weekly.
• Excreta and toe ash were analyzed for nutrient retention and bone mineralization.
• Gross necropsy and histological examination were performed on selected birds.

Main Results:

• Both phytase sources significantly improved body weight gain, feed intake, gain:feed ratio, and nutrient retention (DM, P, Ca).
• Toe ash content and percentage were enhanced by phytase supplementation.
• Phosphorus excretion decreased with increasing phytase levels, reaching a plateau around 2,500 U/kg.
• No adverse effects or abnormalities were observed in gross necropsy or histological evaluations for either phytase source or level.

Conclusions:

• Phytaseed phytase is as effective as Natuphos phytase in improving the performance and nutrient utilization of young broilers fed corn-soybean meal-based diets.
• Phytaseed phytase is safe for use in broiler diets at the tested levels.
• The optimal dose for both phytases appears to be around 2,500 U/kg for maximizing benefits.