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Activation of human leukocytes by acute hypoxia
1Department of Biomedical Sciences, School of Natural & Environmental Sciences, Coventry University, Cox Street Coventry, CV1 5FB, Birmingham, UK.
Experimental Physiology
|May 29, 2000
Abstract:
Exposure of human leukocytes to 12% and 6% O(2) in vitro resulted in striking ultrastructural and morphological changes. These changes included the appearance of crater-like holes, a reduction in granular size and disruption of the cellular membrane. The implications of these findings is discussed.