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A short-term brushing model for assessing antiplaque/antigingivitis dentifrice effectiveness: a pilot study
B Kohut1, J Coelho, N C Sharma
1Warner-Lambert Co., Morris Plains, NJ, USA.
The Journal of Clinical Dentistry
|May 29, 2000
Summary
An essential oil dentifrice significantly reduced plaque, gingivitis, and bleeding in a 3-week pilot study. This short-term brushing model effectively demonstrated the antiplaque and antigingivitis benefits of the formulation.
Area of Science:
- Oral hygiene research
- Clinical dentistry
- Periodontology
Background:
- Supragingival plaque and gingivitis are common oral health issues.
- Assessing the efficacy of dentifrice formulations requires reliable clinical models.
- Short-term models are desirable for efficient product development.
Purpose of the Study:
- To evaluate a 3-week brushing model for assessing dentifrice efficacy.
- To determine the antiplaque and antigingivitis effects of an essential oil dentifrice.
- To assess the inhibition of gingival bleeding by the experimental dentifrice.
Main Methods:
- A double-blind, parallel-group, controlled pilot study.
- 42 subjects used an essential oil dentifrice or vehicle control for 3 weeks.
- Clinical examinations for plaque, gingivitis, and bleeding were performed at baseline and post-treatment.
Main Results:
- The essential oil dentifrice showed statistically significant reductions in plaque (39.6%), gingivitis (10.8%), and bleeding (65.4%) compared to the control.
- No adverse events were reported during the study.
- The 3-week duration was adequate to demonstrate the dentifrice's effectiveness.
Conclusions:
- A 3-week brushing model is effective for evaluating essential oil dentifrices.
- The essential oil formulation demonstrated significant antiplaque, antigingivitis, and anti-bleeding properties.
- Further studies are recommended to confirm reliability and explore formula modifications.