[The mechanisms of insulin resistance during hyperthermia]

Consideration is given to the possibility and mechanisms of insulin resistance as a function of human tolerance to hyperthermia. Poor tolerance of hyperthermia was observed in persons with initially altered metabolism. Administration of sugar test by these persons revealed high levels of insulin incretion and low insulin reactivity of tissues or insulin resistance. Negative effects of extended period of hyperthermia that may bring about pathologic pancreatic changes even in essentially healthy persons are reviewed. Following LCE and rehabilitative therapy, 60% of aviators were medically certified without change in fitness category.