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[The Sharp syndrome ("mixed connective tissue disease")].

M Rosenthal

    Schweizerische Medizinische Wochenschrift
    |January 31, 1976
    PubMed
    Summary

    A new rheumatic disease, mixed connective tissue disease (MCTD), presents with SLE, scleroderma, and polymyositis features. Diagnosis involves specific autoantibodies, and it shows a favorable prognosis with corticosteroid treatment.

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    Area of Science:

    • Rheumatology
    • Immunology
    • Internal Medicine

    Background:

    • Mixed Connective Tissue Disease (MCTD) is a distinct rheumatic condition.
    • It shares features with systemic lupus erythematosus (SLE), progressive systemic sclerosis, and polymyositis.
    • Understanding MCTD is crucial for accurate diagnosis and management of complex autoimmune disorders.