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Suicide and bipolar disorder.

K R Jamison1

  • 1Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

The Journal of Clinical Psychiatry
|May 29, 2000
PubMed
Summary
This summary is machine-generated.

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Suicide is a common outcome for severe psychiatric illnesses, particularly mood disorders like depression and bipolar disorder. Effective treatments, especially lithium, are crucial for reducing suicide rates in these patients.

Area of Science:

  • Psychiatry
  • Neuroscience
  • Mental Health Research

Background:

  • Suicide is a significant concern in patients with severe psychiatric illnesses, most commonly mood disorders.
  • Bipolar disorder presents a high risk, with 25%-50% of patients attempting suicide.
  • Existing treatments for mood disorders have limited known impact on suicide mortality.

Purpose of the Study:

  • To highlight the critical link between mood disorders and suicide.
  • To underscore the need for research into mood-altering treatments' efficacy in reducing suicide.
  • To emphasize the importance of suicide risk assessment in clinical practice.

Main Methods:

  • Literature review on suicide in psychiatric illness.
  • Analysis of existing data on mood disorder treatments and suicide rates.

Related Experiment Videos

  • Clinical assessment protocols for suicidal risk.

    • Main Results:

    • Mood disorders are the most frequent psychiatric conditions linked to suicide.
    • Lithium is the most effective known treatment for reducing suicide.
    • Specific contributions of other mood-altering treatments remain largely unknown.

    Conclusions:

    • Suicide is a complex outcome of severe psychiatric distress, often linked to treatable depression.
    • Further research is needed to identify effective mood-altering treatments for suicide prevention in bipolar depression.
    • Suicide risk assessment is a mandatory first step in treating psychiatric illness.