Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Radiation-induced heart disease.

R Stroobandt, Knieriem H-J, De Wolf

    Acta Cardiologica
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Radiation therapy for breast cancer can cause long-term heart complications. This case study details a patient who developed constrictive pericarditis and myocardial fibrosis years after treatment for breast carcinoma.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A new method of counting reticulocytes using fluorescence microscopy.

    La Presse medicale·2010
    Same author

    Methyldopa in the Treatment of Hypertension.

    British medical journal·2010
    Same author

    Use of an event recorder in the decision for pacemaker implantation in a child with syncope.

    European journal of pediatrics·2002
    Same author

    Supraventricular tachycardia with alternating cycle length: what is the mechanism?

    Journal of cardiovascular electrophysiology·2002
    Same author

    Epidemiology of cancer mortality.

    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie·2001
    Same author

    WHO consensus conference on diet and cancer. Members of the breast cancer panel.

    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)·2000

    Area of Science:

    • Cardiology
    • Oncology
    • Radiology

    Background:

    • A 45-year-old woman received radiation therapy for breast cancer with axillary lymph node metastasis.
    • The heart received a significant radiation dose (4,000 rads) during post-operative treatment.

    Observation:

    • The patient developed radiopneumonia and acute pericarditis symptoms two years post-treatment.
    • Progressive constrictive pericarditis was observed starting in 1972.

    Findings:

    • Pericardiectomy in 1974 revealed thickened pericardium.
    • Histopathological examination showed epicardial, myocardial, and perivascular fibrosis.
    • The diagnosis was post-radiation pericarditis with potential myocardial involvement.

    Implications:

    Related Experiment Videos

    • Radiation-induced cardiac injury, including pericarditis and myocardial fibrosis, can manifest years after treatment.
    • Myocardial involvement may significantly impact the patient's long-term clinical outcome.
    • This case highlights the importance of long-term cardiac monitoring in patients treated with chest radiation.