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Updated: Aug 16, 2026

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
Published on: August 30, 2014
[Vaccination against acute otitis media]
R H Veenhoven1, Y L van den Berg, A G Schilder
1Spaarne Ziekenhuis, afd. Kindergeneeskunde, BR Haarlem.
Insights
Preventing childhood acute otitis media (AOM) is crucial due to high illness rates and antibiotic resistance. Pneumococcal conjugate vaccines reduce some AOM cases, especially for children with recurrent ear infections.
Area of Science:
- Pediatrics
- Infectious Diseases
- Vaccinology
Context:
- Acute otitis media (AOM) is the most common bacterial infection in children.
- Rising antibiotic resistance in Streptococcus pneumoniae, a primary AOM pathogen, necessitates prevention strategies.
- High morbidity and healthcare costs associated with AOM underscore the need for effective interventions.
Purpose:
- To evaluate the impact of pneumococcal conjugate vaccines on the incidence of acute otitis media.
- To assess the effectiveness of vaccination in preventing AOM, particularly in children with recurrent infections.
Summary:
- Pneumococcal conjugate vaccines decrease AOM cases linked to vaccine serotypes.
- Overall AOM incidence reduction is less than 10% despite vaccination.
- Children experiencing recurrent AOM episodes may derive greater benefit from these vaccines.
Impact:
- Vaccination strategies can help mitigate the burden of AOM in pediatric populations.
- Further research may be needed to enhance vaccine efficacy against non-vaccine serotypes and overall AOM prevention.
- Understanding vaccine impact on recurrent AOM is key for targeted public health initiatives.
Abstract:
Acute otitis media (AOM) is the most frequent bacterial infection in childhood. Because of the high morbidity, the costs of AOM and growing concern about increasing resistance of pneumococci, the most common bacterial cause of AOM, prevention of AOM is important. Vaccination with the recently developed pneumococcal conjugate vaccines leads to a reduction in the number of AOM cases caused by the serotypes present in the vaccine, but the reduction in overall AOM incidence is below 10%. In particular the children with recurrent episodes of AOM may benefit more from these pneumococcal conjugate vaccines.
Related Concept Videos
Vaccinations
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Tonsillitis II: Management
Poliomyelitis
Respiratory Syncytial Virus Disease

