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Computerised evaluation of cognitive and motor function.

B Kisacanin¹, G C Agarwal, J Taber

¹Dept. EECS, University of Illinois at Chicago, USA. bkisacan@mail.delcoelect.com

Medical & Biological Engineering & Computing

|June 1, 2000

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Computerised tracking tests show promise for evaluating antiepileptic drug (AED) effectiveness and monitoring Alzheimer's disease (AD) progression. These reliable and sensitive tests offer a valuable tool for clinical assessments in neurology.

Area of Science:

Neuroscience
Clinical Neurology
Medical Technology

Background:

Computerised tracking offers a novel method for assessing cognitive and motor functions.
Evaluating the efficacy of antiepileptic drugs (AEDs) and monitoring Alzheimer's disease (AD) progression requires sensitive and reliable assessment tools.

Purpose of the Study:

To evaluate the utility of computerised tracking in assessing AED effectiveness in epilepsy patients.
To investigate the application of computerised tracking for monitoring Alzheimer's disease progression.
To introduce real-time target speed adaptation and signal-processing techniques to simplify experimental protocols.

Main Methods:

Clinical study comparing AED blood levels, standard neuropsychological tests, and computerised tracking/reaction time tests in epilepsy patients.

Related Experiment Videos

Implementation of real-time target speed adaptation to streamline experiments.

Application of signal-processing techniques to analyze computerised tracking data for AD patients.

Main Results:

Computerised tracking tests demonstrated repeatability, reliability, and sensitivity, indicating their utility in epilepsy treatment evaluation.
Variations in optimal speed (OS) were observed within the therapeutic range of AEDs.
Signal-processing analysis revealed distinct tracking characteristics in AD patients, mirroring healthy controls' non-preview tracking due to impaired working memory.

Conclusions:

Computerised tracking is a reliable and sensitive tool for evaluating epilepsy treatment and monitoring AD progression.
The study highlights the potential of adapted computerised tracking protocols for clinical neurological assessments.
Impaired working memory in AD significantly influences motor planning and tracking behavior, as evidenced by the observed tracking modes.