Related Experiment Video
Updated: Oct 16, 2026

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
[Silica urolithiasis: report of a new case]
N A Cruz Guerra1, M A Gómez García, F Lovaco Castellano
1Servicio de Urología, Hospital Ramón y Cajal, Madrid.
Abstract:
We report a new case of silica urolithiasis in a 71-year-old patient with background of medicament ingesta (antacid) which could justify the formation of these calculi with so uncommon composition. Medicament calculi amounts about 1% from total urinary calculi. Among them, silica ones (silicon dioxide or Si O2) have been relate din their etiology to chronical ingest of antacid drugs, specially those with magnesium trisilicate. Silica formation in urine is facilitated and conditioned by an acid pH of it. Diagnosis and therapeutical approach does not change in relation to other lithiasis with similar dimension or location. After its composition report, and ruling out the possibility for patient's malingering, urine alkalinization was applied, with an excellent follow-up afterwards. The antacid was substituted by other drug. We analyze the most important aspects about this case. We also make reference to the main related bibliography.
Related Concept Videos
Urinary Tract Calculi I: Introduction
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Urinary Tract Calculi V: Nursing Management
Urinary Tract Calculi VI: Surgical Management
Urinary Tract Calculi IV: Nutrition Therapy and Prevention