Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Spectral estimators in elastography.

E E Konofagou1, T Varghese, J Ophir

  • 1Department of Radiology, University of Texas Medical School, Houston 77030, USA. elisak@bwh.harvard.edu

Ultrasonics
|June 1, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Natural aging and Alzheimer's disease pathology increase susceptibility to focused ultrasound-induced blood-brain barrier opening.

Scientific reports·2023
Same author

Long term study of motivational and cognitive effects of low-intensity focused ultrasound neuromodulation in the dorsal striatum of nonhuman primates.

Brain stimulation·2022
Same author

Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons.

Molecular and cellular neurosciences·2020
Same author

<i>In vivo</i> carotid strain imaging using principal strains in longitudinal view.

Biomedical physics & engineering express·2019
Same author

A Cross-Sectional Investigation of Cognition and Ultrasound-Based Vascular Strain Indices.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists·2019
Same author

Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles.

Physics in medicine and biology·2018
Same journal

Grain size evaluation in polycrystalline materials using the interference effect of bounded ultrasonic beams at the Rayleigh critical angle.

Ultrasonics·2026
Same journal

Ultrasonic characterization of functionally graded materials using a continuously graded model and spectral inversion.

Ultrasonics·2026
Same journal

Frequency-wavenumber domain inversion for arterial viscoelasticity.

Ultrasonics·2026
Same journal

Pressure- and frequency-dependent acoustic behavior of second-generation acoustic reporter genes-expressing bacteria for optimized ultrasound imaging.

Ultrasonics·2026
Same journal

Laser ultrasonic detection for strut defects in additively manufactured lattice structure using zero-group-velocity Lamb waves.

Ultrasonics·2026
Same journal

A hemispherical bubble induced by ultrasonic vibration observed by high-speed X-ray imaging.

Ultrasonics·2026
See all related articles

Tissue strain can be measured directly using spectral analysis of ultrasound echo signals, offering a more robust alternative to traditional time delay elastography methods.

Area of Science:

  • Ultrasound medical imaging
  • Biomedical engineering
  • Medical physics

Background:

  • Elastography traditionally measures tissue strain indirectly via time delay techniques.
  • Time scaling in ultrasound signals is often treated as distortion.
  • Recent findings suggest time scaling can be directly estimated as strain.

Purpose of the Study:

  • To introduce and compare spectral strain estimation methods with traditional time delay elastography.
  • To evaluate the robustness and precision of spectral techniques for strain measurement.

Main Methods:

  • Developed two strain estimators based on Doppler-like frequency shifts and spectral bandwidth changes.
  • Compared spectral methods against traditional time delay estimators.
  • Validated findings through both simulations and experimental data.

Related Experiment Videos

Main Results:

  • Spectral strain estimation provides a direct measure of tissue strain.
  • Frequency shift strain estimators demonstrate increased robustness compared to time delay methods.
  • Robustness is attributed to spectral techniques' insensitivity to phase decorrelation noise.

Conclusions:

  • Spectral methods offer a more robust approach to ultrasound elastography.
  • While less precise than time delay methods, spectral techniques are superior in noisy environments.
  • This study validates the use of spectral analysis for direct and reliable strain estimation.