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Infantile pseudotumor cerebri related to viral illness

S K Tamer1, U Tamer, P Warey

  • 1Department of Pediatrics, JLN Hospital & Research Centre, Bhilai, Madhya Pradesh.

Indian Journal of Pediatrics
|September 1, 1996
PubMed

Insights

Infant pseudotumor cerebri (PTC) cases occurred in seasonal clusters, linked to viral illness. This specific form of PTC in infants demonstrated a benign outcome, differing from typical presentations.

Area of Science:

  • Pediatrics
  • Neurology
  • Infectious Diseases

Background:

  • Pseudotumor cerebri (PTC) is characterized by diverse symptoms, associated conditions, and variable patient outcomes.
  • Previous observations of PTC in children have not highlighted specific seasonal clustering, infant-only demographics, or strong links to viral infections.

Purpose of the Study:

  • To present preliminary observations on a peculiar form of pseudotumor cerebri (PTC) observed in infants.
  • To investigate the unique clinical characteristics, seasonal patterns, and outcomes of this infant PTC presentation.

Main Methods:

  • Hospitalization and evaluation of children presenting with signs of increased intracranial pressure (ICP).
  • Diagnostic procedures included lumbar puncture, cranial ultrasonography, CT scans, and culture studies.
  • Data collection focused on clinical manifestations, demographic information, seasonal occurrence, and family history of viral illness.

Main Results:

  • Fifteen infants (male-female ratio 2:3) presented with PTC, with 73.3% occurring in clusters during late summer and early fall.
  • Common symptoms included bulging fontanelle, vomiting, fever, and signs of respiratory infection, diarrhea, or skin rashes.
  • Lumbar puncture consistently revealed high cerebrospinal fluid (CSF) pressure in all cases, with 73.3% having a history of contact with viral illness.

Conclusions:

  • The study suggests a distinct form of pseudotumor cerebri (PTC) recently observed in infants.
  • This infant PTC appears closely associated with viral illnesses and exhibits a notably benign clinical outcome.
  • Further research is warranted to understand the specific mechanisms and long-term implications of this pediatric PTC variant.

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