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Related Experiment Videos

Overnight orthokeratology.

J J Nichols1, M M Marsich, M Nguyen

  • 1The Ohio State University, College of Optometry, Columbus 43210-1240, USA. nichols.142@osu.edu

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|June 1, 2000
PubMed
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Overnight orthokeratology effectively reduces myopia temporarily. This method, using reverse geometry rigid gas-permeable contact lenses, leads to significant visual and refractive improvements, with corneal remodeling observed.

Area of Science:

  • Ophthalmology
  • Optometry
  • Corneal Physiology

Background:

  • Orthokeratology offers temporary myopia reduction via rigid gas-permeable contact lenses.
  • Advancements in lens design and materials have revitalized interest in orthokeratology.

Purpose of the Study:

  • To evaluate visual, refractive, topographic, and corneal thickness changes during overnight orthokeratology.
  • To assess the efficacy and stability of overnight orthokeratology over 60 days.

Main Methods:

  • Ten myopic subjects underwent a 60-day trial of overnight orthokeratology with reverse geometry lenses.
  • Evaluations included visual acuity (high/low contrast), refraction, corneal topography, and thickness measurements.
  • Examinations were conducted on days 1, 7, 14, 30, and 60, with multiple measurements per day.

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Main Results:

  • Significant improvements in uncorrected visual acuity (high and low contrast) were observed by day 7 and sustained for 8 hours.
  • Mean reduction in high-contrast visual acuity was -0.55 logMAR (20/19), and low-contrast was -0.48 logMAR (20/33) at day 60.
  • Corneal topography showed central flattening, and central corneal thickness decreased by an average of 12 micrometers, indicating corneal remodeling.

Conclusions:

  • Overnight orthokeratology is an effective method for temporary myopia reduction.
  • The study suggests corneal remodeling, evidenced by central thinning, is the mechanism behind myopia reduction.
  • The visual, refractive, and topographic effects were stable throughout an 8-hour daytime period.