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Updated: Aug 9, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
Published on: November 24, 2014
Aortocoronary artery bypass: present indications and risk factors
Insights
Coronary artery bypass surgery is effective for patients with severe coronary artery disease. Poor ventricular function and diffuse disease are key factors in mortality, suggesting broader recommendations for bypass surgery.
Area of Science:
- Cardiovascular Surgery
- Cardiology
- Clinical Outcomes
Background:
- Coronary artery occlusive disease necessitates surgical intervention for many patients.
- Surgical outcomes depend on patient-specific risk factors and disease severity.
Purpose of the Study:
- To analyze the outcomes of coronary artery bypass surgery in a consecutive patient series.
- To identify risk factors associated with early mortality and perioperative complications.
Main Methods:
- Retrospective analysis of 275 patients undergoing coronary artery bypass surgery in 1974.
- Evaluation of patient demographics, cardiac function, and coronary artery disease extent.
- Assessment of early mortality and perioperative myocardial infarction rates.
Main Results:
- Overall mortality was 1.8%, with perioperative myocardial infarction in 3.6% of patients.
- Significant risk factors for mortality included diffuse coronary arteriosclerosis and impaired left ventricular function.
- Patients over 60, those with New York Heart Association functional class IV, left main coronary artery stenosis, and preinfarction angina were identified.
Conclusions:
- Diffuse coronary arteriosclerosis and poor ventricular function are critical determinants of outcomes, often leading to incomplete revascularization.
- Coronary artery bypass grafting is recommended for patients with intractable angina, impaired left ventricular function, and even asymptomatic individuals with positive stress electrocardiograms.
Abstract:
From 1969 through 1974, a total of 4,522 patients were operated on for coronary artery occlusive disease. This article is an in-depth analysis of a consecutive series of 275 of these patients, operated on during 1974. The mortality was 1.8% and perioperative myocardial infarction occurred in 3.6%. On analysis of risk factors, it was found that 24% of the patients were over the age of 60; 57% had some degree of left ventricular dysfunction; 9% had generalized hypokinesis; 24% were New York Heart Association functional class IV; 13% had left main coronary artery stenosis; and 11% had preinfarction angina. On analysis of the early mortality, the limiting factor was diffuse coronary arteriosclerosis combined with poor ventricular function. This resulted in inadequate or incomplete myocardial revascularization. Since these two risk factors are usually predictable, coronary artery bypass can be recommended not only for patients with intractable angina, but also for patients with impaired left ventricular function associated with angina, and in patients without angina who have a positive stress electrocardiogram.
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