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Related Experiment Videos

[Carcinoid of the appendix. A case report].

S I Spallitta1, G Termine, M Stella

  • 1Divisione di Chirurgia d'Urgenza, Azienda Ospedaliera V. Cervello, Palermo.

Minerva Chirurgica
|June 1, 2000
PubMed
Summary

Appendiceal carcinoid tumors are rare but can be incidentally found during appendectomies. Treatment depends on tumor size and invasion, with a generally good prognosis for carcinoid tumors.

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Carcinoid tumors of the appendix are uncommon, occurring in 1 in 200-300 appendectomies.
  • These tumors are more prevalent in women and typically located at the appendix tip, often smaller than 1 cm.

Observation:

  • Diagnosis is frequently incidental, occurring post-appendectomy for acute appendicitis.
  • While rare, liver metastases can occur, particularly with larger tumors (>2 cm), potentially leading to carcinoid syndrome.

Findings:

  • Treatment strategies vary by tumor size: simple appendectomy for <1 cm, right hemicolectomy for >2 cm.
  • Controversy exists for 1-2 cm tumors; appendectomy may suffice unless mesoappendiceal invasion is present.
  • Positive surgical margins necessitate further surgical intervention.

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Implications:

  • Accurate diagnosis and staging, aided by imaging (CT, US) and biomarkers (5-HIAA), are crucial for treatment planning.
  • 111In-octreotide scintigraphy shows high sensitivity for carcinoid detection and staging.
  • Appendiceal carcinoid tumors generally have a favorable prognosis (5-year survival 85.9-100%), with octreotide managing metastatic symptoms.