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Related Experiment Videos

A devastating ocular pathogen: beta-streptococcus Group G.

D C Ritterband1, M K Shah, D J Buxton

  • 1Department of Ophthalmology, The New York Eye and Ear Infirmary, New York 10003, USA.

Cornea
|June 1, 2000
PubMed
Summary
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Group G beta-hemolytic Streptococcus (BHS-G) can cause severe ocular infections like endophthalmitis and keratitis. These infections present rapidly with intense inflammation and often respond poorly to antibiotics.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Group G beta-hemolytic Streptococcus (BHS-G) is an uncommon cause of ocular infections.
  • This study reports on four cases of BHS-G ocular infections, including endophthalmitis and keratitis.

Observation:

  • Three of the four patients experienced fulminant infections within 12 hours of symptom onset.
  • Infections arose from diverse sources, including contaminated donor buttons, post-cataract surgery, suture tracts, and direct trauma.
  • Clinical presentations ranged from severe endophthalmitis with vision loss to keratitis with stromal loss.

Findings:

  • BHS-G ocular infections are characterized by rapid onset and extreme inflammation.
  • Despite in vitro antibiotic sensitivity, treatment response was often poor or slow.

Related Experiment Videos

  • Severe outcomes included vision loss and evisceration in one case.

    • Implications:

    • Early recognition and aggressive management are crucial for BHS-G ocular infections.
    • The poor response to antibiotics highlights the need for further research into optimal treatment strategies.
    • This case series expands the understanding of BHS-G as a potential pathogen in serious eye infections.