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Human leukocyte antigen-G: immunotolerant major histocompatibility complex molecule in transplantation
I Khalil-Daher1, N Rouas-Freiss, E D Carosella
1Service de Recherches en Hémato-Immunologie, CEA/DRM/DSV, Hôpital Saint-Louis, Paris, France.
World Journal of Surgery
|June 1, 2000
Abstract:
HLA-G is a nonclassical major histocompatibility complex class I molecule selectively expressed on cytotrophoblasts at the fetal-maternal interface, where it plays a role in maternofetal tolerance. In this review, attempts were made to summarize the current state of knowledge of the effects of HLA-G on both natural killer cell and T cell functions and their implications in transplantation.