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In Utero Intra-cardiac Tomato-lectin Injections on Mouse Embryos to Gauge Renal Blood Flow

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Intravascular papillary endothelial hyperplasia in the kidney of a child.

H S Kim¹, E J Park, J H Lee

¹Department of Pathology, Chonnam National University Medical School, Chonnam University Research Institute of Medical Science, Kwangju, Republic of Korea.

Virchows Archiv : an International Journal of Pathology

|June 2, 2000

Summary

Intravascular papillary endothelial hyperplasia (IPEH), a benign vascular lesion, was identified in a child's kidney. This rare case report details its radiological and pathological features in a pediatric patient.

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Area of Science:

Vascular Pathology
Pediatric Nephrology
Surgical Pathology

Background:

Intravascular papillary endothelial hyperplasia (IPEH) is a rare, benign vascular lesion.
IPEH is often considered an unusual manifestation of an organizing thrombus.
Renal involvement of IPEH is uncommon, particularly in pediatric cases.

Observation:

A 7-year-old girl presented with flank pain and gross hematuria.
Radiological imaging revealed well-defined hypoechoic lesions in the left kidney's medulla.
Gross examination showed a sponge-like, intravascular mass with papillary fronds.

Findings:

Histopathological analysis confirmed the presence of papillary fronds lined by benign endothelial cells.
The intravascular mass was encased by a fibrous capsule.
This represents the first documented pediatric case of renal IPEH.

Implications:

This case expands the known spectrum of renal lesions in children.
Accurate diagnosis of renal IPEH is crucial to differentiate it from malignant tumors.
Further understanding of IPEH in pediatric renal pathology is warranted.