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Quantification of carotid stenoses using 3D morphometer, CT angiography and conventional angiography
1Service de Chirurgie Vasculaire, Service de Radiologie, Hôpital sud-Rennes, France.
The Journal of Cardiovascular Surgery
|June 3, 2000
Summary
Three-dimensional morphometry (M3D) shows uncertain reliability for quantifying carotid stenosis compared to conventional angiography. Spiral CT scans offer easier quantification via slices, especially for calcified lesions, but M3D may be useful post-treatment with technical adaptations.
Area of Science:
- Medical Imaging
- Vascular Surgery
- Quantitative Analysis
Background:
- Extracranial carotid stenosis diagnosis relies on accurate quantification.
- Conventional 2D angiography is the reference standard but is invasive.
- Novel 3D imaging techniques require validation against established methods.
Purpose of the Study:
- To compare the performance of a 3D morphometer (M3D) against 2D conventional angiography and spiral CT for quantifying extracranial carotid stenoses.
Main Methods:
- A prospective study included 15 patients with symptomatic carotid lesions.
- Carotid bifurcations were analyzed using M3D, 2D angiography, and spiral CT.
- Measurements included diameters (MIP technique) and surfaces (reformatted axial slices) using the NASCET method.
Main Results:
- M3D showed good correlation with angiography in 69% of cases (MIP technique).
- Spiral CT correlated with angiography in 47% (MIP) but improved to 79% with reformatted slices.
- CT quantification was hindered by calcified stenoses in 8/10 MIP and 2/10 slice-based measures.
Conclusions:
- The reliability of 3D morphometry for stenosis quantification is currently uncertain.
- Spiral CT quantification is more feasible using planimetry on reformatted slices.
- M3D may be a viable alternative to selective angiography post-treatment, pending technical improvements and larger acquisition fields.